The injectable drug delivery devices market consists of sales of injectable drug delivery devices and related products such as conventional syringes, needle-free injectors, auto injectors and pen injectors by entities (organizations, sole traders, and partnerships). The market includes the sales of the injectable devices that have been extensively utilized for various routes of drug administration, such as intravenous, subcutaneous, intradermal, intra-peritoneal, and intra-muscular and others to treat medical conditions ranging from cancer, diabetes to autoimmune disorders.

The dental services market consists of sales of dental services and related goods by entities (organizations, sole traders and partnerships) that provide general dentistry, oral surgeries and orthodontics and prosthodontic services. This industry comprises establishments of licensed health practitioners having the degree of D.M.D. – Doctor of Dental Medicine, D.D.S. – Doctor of Dental Surgery, or D.D.Sc. – Doctor of Dental Science. Dentists are health practitioners who operate private or group practices in their own premises or in other facilities such as hospitals or health maintenance organization (HMO) medical centers. Dental e services include, dental consultations, oral examinations, preventive, promotive, curative and restorative dentistry.iThey may also specialize in a specific field of dentistry such as implants, replacements or restorations.

Herpes is a contagious infection caused by the HSV. It is transmitted through sexual contact (infected fluids) or direct contact with infected skin (open wounds). It often manifests as pain and blisters around the mouth and external genitalia. Other herpes symptoms include itching, fever, chills, body ache, and pain and discomfort when urinating. HSV infection, commonly known as herpes infection, can be caused by either HSV-1 or HSV-2. HSV-1 infections are the most common as they spread by oral to oral contact, which can cause oral herpes. However, most are sub-clinical and asymptomatic. In symptomatic cases, the HSV-1 can cause mild to severe illnesses. Infections often manifest as cold sores but can also cause herpes sores, gingival aphthous ulcer, meningitis, encephalitis, corneal blindness, and neonatal herpes. The clinical manifestations of HSV-1 are determined by the site of initial entry of the virus.

Crohn’s disease is a chronic inflammatory bowel disease (IBD) in which abnormal reactions of the immune system causes inflammation on the inner lining of small and large intestines. It is also called as Regional Enteritis. The four main forms of Crohn’s disease are: 1) Ileocolitis ; 2) Ileitis; 3) Gastroduodenal ; 4) Jejunoileitis Ileocolitis: Inflammation occurs in the small intestine and part of the large intestine, or colon. Ileocolitis is the most common type of Crohn’s disease.

Cervical cancer is a type of cancer that occurs in the cells of the cervix — the lower part of the uterus that connects to the vagina. The three main forms of cervical cancer are: 1) Squamous ; 2) Adenocarcinoma; 3) Squamous-Adenocarcinoma.

The presence of life science companies such as pharmaceutical and biotechnology firms, academic and research institutes, and government organizations has witnessed a rapid increase worldwide. Also, the rise in the adoption of decentralized clinical trials, high focus on R&D activities, the surge in demand for specialty medicines, and real-world evidence are expected to propel the adoption of clinical trial outsourcing services worldwide.

Traditionally, biopharmaceutical excipients are inert components used in medicines. They are crucial to guarantee the high quality, safety, and efficacy of a drug. These are substances other than the active drug, which are included during the manufacturing process or are contained in the finished pharmaceutical dosage form. Despite being regarded as therapeutically inert, they are essential to transport the active drug to a location in the body where the drug is intended to show its action. In addition, biopharmaceutical excipients are key elements to ensure the adequate processability or stabilization of the drug substance.

Biologics or biological drugs are obtained from living organisms, such as humans, animals, and microorganisms, using complex manufacturing processes and are administered closely under monitored conditions. They contrast with traditional non-biological drugs that are synthesized in laboratories using chemical processes without the use of biological components. Cancer, infectious diseases, and autoimmune diseases are those diseases that the bio pharmacy is used to prevent, treat, or cure. Biologics bring hope for treatments for diseases such as cancer, heart disease, Alzheimer's, diabetes, and rheumatoid arthritis. Biopharmaceuticals have a few side effects and promise targeted treatments with provisional measures for personalized medicine, but this area is still in its infancy.

The Psoriatic Arthritis clinical trial portfolio comprises approximately 139+ trials which are sponsored by various vendors. Interleukin inhibitors (42.31%) are the major mechanism of action of drugs which are under investigation in various development phases. Approximately 90-95% of clinical trials which are being under investigation as monotherapies therapies. Johnson & Johnson is the top sponsor for Psoriatic Arthritis-related ongoing clinical trials. Novartis AG, Amgen Inc, Bristol-Myers Squibb Co, and Pfizer Inc are among other notable clinical trial sponsors involved in Psoriatic Arthritis.

集采、国谈为本季度热点话题，关注相关进展。第七批国采中选率超70%，平均降幅48%；集采购品种可替代药品参考监测范围重磅文件在业内流出；第1-4 批国采续约工作陆续开展；医保目录调整正式启动，预计11-12 月将公布结果；双通道政策在各省间进一步落实；地方增补医保目录的消化工作接近尾声；器械集采稳步推进，脊柱、冠脉、种植牙等集采进入常态。