Malocclusion is the misalignment problem of teeth or incorrect relation between the teeth that can lead to serious oral health conditions. In dental terminology, malocclusion is often referred to as crowded teeth, crossbite, overbite, underbite, and open bite. Usually, malocclusion is an inherited tooth condition, that can be passed down from one generation to the next. It may also be caused by a size difference of the upper and lower jaws or between the jaw and tooth size.

The overall number of sleep and bedding systems (including the mattress) that are used will have a direct impact on the health (cardiovascular health, blood pressure, muscle strength, back and spine problems, and stress levels) of the individual. Hence, the mattress that provides good rest is sought after. The idea of using top-quality mattresses for good sleep is gaining traction among the people, and the increased awareness about the health benefits of better sleep is driving them to buy the orthopedic mattress over regular mattresses.

The report provides market dynamics and trends related to the global psoriatic arthritis treatment market. In addition, it presents the estimations and forecast of the market. The study estimates the revenue generated from the sales of psoriatic arthritis treatment drugs; however, it excludes the psoriatic arthritis treatment service revenue. The valuations comprise revenue generated from psoriatic arthritis treatment drug types such as NSAIDs, DMARDs, biologics, and others that are used for treatment of psoriatic arthritis. Furthermore, the report excludes revenue generated from post-sale services of psoriatic arthritis treatment drugs.

The report provides market dynamics and trends related to the global prostate cancer treatment market. In addition, it presents the estimations and forecast of the market. The valuations comprise revenue generated from prostate cancer treatment drug type such as hormone therapy, biological therapy, chemotherapy, and others. The study estimates the revenue generated from the sales of prostate cancer treatment drugs; however, it excludes the prostate cancer treatment service revenue. Furthermore, the report excludes revenue generated from post-sale services of prostate cancer treatment products.

Transplantation is a process of transferring human cells, tissue or organs from a donor’s body to recipients’ body with the objective of restoring function(s) in the patient’s body. Organ failure can be caused by many diseases, including heart disease, diabetes, hepatitis, cystic fibrosis, and cirrhosis. In addition, injury and birth defects may also lead to organ failure. Organ transplantation is one of the most successful processes in medical history and majorly divided into

WHO于3月11日宣布COVID-19成为大流行病，主要因海外众多国家出现疫情爆发和流行；受疫情本身快速增长以及对经济冲击的双重影响，海外市场出现巨幅震荡，美国股市在三天之内两次向下熔断（-7%），全球多国央行紧急降息也未能阻止下跌趋势。而中国初期管控措施较为严格，成功遏制了本土传播势头，社会生产生活有序恢复；A股市场相对全球出现显著超额收益，医药板块在市场剧烈震荡中表现相对稳健，体现出较好的防御性和相对收益。我们预计在未来1-2周，欧美主要国家将面临非常大的疫情压力，全球金融市场仍将对疫情保持高度敏感，不排除更严重后果的可能性。

全球市场对CAR-T 产品关注度和研究热情逐渐升温，CAR-T 产品的潜在疗效也逐渐被挖掘并且已经有两款产品进入了市场同时实现了规模销售，进一步带动了行业的研究热情。目前CAR-T 的研究领域正在从单一的血液肿瘤应用向多类型肿瘤应用进展，未来的市场空间潜力十足。在这场全球瞩目的CAR-T 研究浪潮中，中国和美国作为CAR-T 领域的主要参与者，将会是引领CAR-T 行业发展的有力推动者。而CAR-T 产品的研发与进展也将会成为国内药企向创新型药企转型的一个重要的里程碑，并促进创新药物和创新支付体系的发展。

国际主要市场均受到疫情的恐慌性影响大幅下跌，上周上证指数下跌5.3%，医药下跌7.56%，跌幅居前四，疫情概念股出现分化，部分疫情概念股调整幅度较大，比如联环药业、鲁抗医药、香雪制药、博雅生物、凯普生物、华大基因、鱼跃医疗等。也有部分疫情概念股表现较好，主要是防疫物质生产方面有新进展或是出口相关，如尚荣医疗、振德医疗、翰宇药业；试剂方面达安基因，美康生物；设备仪器方面九安医疗、宝莱特、理邦仪器。疫情概念股分化反映了市场认识的分化，一方面从国内来看，疫情全面遏制，快速结束；一方面从国际来看，疫情愈演愈烈，发展迅猛，带来出口需求。

2 月我国共批签发血制品1034.60 万瓶，同比增长202.55%，1-2 月共批签发血制品1795.15 万瓶，同比增长75.80%。从各品种血制品批签发情况来看，2 月白蛋白批签发占比64%，静丙批签发占比15%。1-2 月白蛋白批签发占比62%，静丙批签发占比14%。

新冠肺炎全球爆发，ICU 支持不可或缺。截至3 月16 日，海外（除中国外）已经累计确诊101251 例新冠肺炎，累计死亡3937 例。已经有6 个国家累计感染人数超过5000 人，疫情最严重的国家为意大利(27980 例)，伊朗(14991 例)，西班牙(9942 例)，韩国(8320 例)，德国(7272 例)，法国(6633 例)。新冠肺炎疫情在亚洲多国爆发后，欧洲已经成为了新的疫情重灾区。依托ICU 进行重症、危重症诊疗，呼吸机、人工肺为重要设备。由于缺乏抗病毒特效药，新冠肺炎患者的治疗以对症治疗为主，针对性的使用药物及其他支持手段。针对重型患者，推荐使用氧疗与检测，同时注重合并感染的治疗；针对危重患者重点进行呼吸支持，如果肺保护性通气策略失败，则使用体外膜肺氧合（ECMO）治疗，同时辅以更加精细化的对症手段。