关键词：脱氧核糖核酸；遗传学；前列腺癌；医药

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Hemorrhage is a leading cause of deaths on the battlefield. An understanding of the mechanisms and modulators of coagulopathy under conditions soldiers currently experience on the battlefield is important for improved treatment of the hemorrhaging soldier. The global objective of this project tests the hypothesis that environmental and physiological conditions a soldier experiences on the battlefield alters hemodynamic and hemostatic function (i.e., coagulation and fibrinolysis). During the current funding period, we sought to obtain the required IRB and ORP approvals, acquire the necessary equipment to accomplish the stated aims, and complete the objectives in specific aim 1. Aim 1 tests the hypothesis that passive heat stress alters hemostatic function during simulated hemorrhage. ORP documents were submitted for initial administrative review April 4, 2012 and final approval was granted October 10, 2012. Data collection began November 7, 2012. Each subject completes a normothermic and heat stress trial (both including a hemorrhagic challenge), separated by at least 60 days (owing to the amount of blood drawn for each trial). 10 subjects have completed both trials, with the final 2 subjects completing their second trial this May. Data from blood based assays of hemostatic function are presently being processed, while plasma-based assays are expected to be run by Dr. Cap s laboratory at the US Army Institute of Surgical Research by August 2013.

关键词：血液凝固；出血；血液循环；医药

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During the research period, we have successfully achieved our goals of demonstrating IL6R in the ovarian tumor microenvironment and identifying the differentially-spliced isoform as being prominent. In addition, we have demonstrated an important relationship between IL6R expression and the earliest steps in metastasis of ovarian cancer. Both tumor cells and host myeloid cells contribute to IL6R expression within a tumor, thus providing multiple targets for intervening in ovarian cancer metastasis. Our continuing studies will identify the mechanism by which IL6R influences metastasis and opportunities for preventing or reducing this outcome.

关键词：卵巢癌的细胞（生物学）；生长（生理学）；炎症；医药

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During 1994, the Alaska Volcano Observatory (AVO) responded to eruptions, possible eruptions, or false alarms at nine volcanic centers--Mount Sanford, Iliamna, the Katmai group, Kupreanof, Mount Veniaminof, Shishaldin, Makushin, Mount Cleveland and Kanaga. Of these volcanoes, AVO has a real time, continuously recording seismic network only at Iliamna, which is located in the Cook Inlet area of south-central Alaska. AVO has dialup access to seismic data from a 5-station network in the general region of the Katmai group of volcanoes. The remaining unmonitored volcanoes are located in sparsely populated areas of the Wrangell Mountains, the Alaska Peninsula, and the Aleutian Islands (fig. 1). For these volcanoes, the AVO monitoring program relies chiefly on receipt of pilot reports, observations of local residents and analysis of satellite imagery.

关键词：阿拉斯加火山；地震；阿拉斯加火山观测站（AVO）

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No abstract available.

关键词：用药；健康物质的使用；精神障碍；医药

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Focusing on the U.S. sulfur dioxide (SO2) allowance market from its inception (in 1994) to 2009, we model allowance prices to determine the influence of market fundamentals such as prices of high- and low-sulfur coalon allowance price level and volatility. Our empirical analysis finds that the SO2 market, similar to other emission markets studied in the literature, had relatively weak influence of market fundamentals for several years after launch that is, allowance prices did not reflect marginal abatement costs for the first several years of operation. However, we find evidence of increased influence of market fundamentals after the first few years of the program but before a court decision that introduced significant uncertainty into the market in mid-2008. We also find that market volatility increased in response to all types of communications from the administrator, suggesting that the development of a formal communication strategy, possibly similar to the strategy used by central banks, would reduce price volatility and increase the efficiency of the market.

关键词：配额市场；银行；通信

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Mobile devices provide civilians with a convenient way to communicate on a day-to-day basis. However, their centralized infrastructure can be interrupted at critical times such as during natural disasters. While this cellular infrastructure may not be available in environments, such as the battlefield, these ubiquitous devices could exploit ad-hoc mode communication to be of use. The Army has identified several military applications for ad-hoc networks of mobile devices, including communication between dismounted Soldiers, facial recognition, and situation awareness. Many of these applications require more capabilities than most mobile devices possess, or would prove to be a burden on the limited battery lives of these devices. Thus, offloading computation to a more capable machine has been identified as a means to make these devices useful while mitigating their weaknesses. This has lead Army researchers to develop novel algorithms to improve the offloading process. Although these algorithms have been tested via simulation, a working implementation is necessary to fully evaluate them. This report discusses the state of ad-hoc mode communication on Android devices, and describes the procedure for enabling ad-hoc mode, which is often not available by default. It goes on to describe techniques for studying multiple aspects of the network and its behavior.

关键词：算法；机器人；蜂窝通信；通信和无线电系统

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The report presents the results of a survey of safety culture in three Norwegian haulier companies, which are selected based on an assumption that they have good safety culture. The study supports the assertion that the companies have good safety cultures. This especially applies to Company A, which has the highest safety culture score of the three companies, and which also have a higher safety culture score than we have found in other transport sectors. This is probably due to the fact that Company A transports dangerous goods, which is a line of transport which has particular framework conditions favoring safety. The accident involvement of the drivers were in accordance with the companies score on the safety culture index. Analyzing the data on the three companies work on safety, we have identified the following common characteristics of good safety work in haulier companies: 1) Follow up of drivers speed, seat belt use and driving style, 2) Managers and employees safety commitment, 3) Predictability, 4) Organization of transport assignments, 5) Pay system, 6) Control of drivers compliance with regulations related to drive and rest, 7) Safety training/education, 8) Arenas for communication about safety, 9) Reporting culture and systems, and 10) Safety management system: a) risk analyses, b) procedures, c) training.

关键词：公路安全；公路运输；公路使用；通信

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Catalytic converters (CATCONs) are required by Federal law to be installed in nearly all gasoline- and diesel-fueled onroad vehicles used in the United States. About 85 percent of the light-duty vehicles and trucks manufactured worldwide are equipped with CATCONs (Ashok Kumar, Director, A1 Specialized Services & Supplies, Inc., written commun. July 10, 2012). These vehicles include buses, cars, light- and heavy-duty trucks, and motorcycles. Many offroad vehicles, such as trail bikes and all-terrain recreational vehicles, are also equipped with CATCONs, but offroad vehicles are not addressed in this paper (Manufacturers of Emission Controls Association, 2008). Portions of the CATCONs (called monoliths) are recycled for their platinum-group metal (PGM) content and for the value of the stainless steel they contain. The cerium contained in the monoliths, however, is disposed of along with the slag produced from the recycling process. Although there is some smelter capacity in the United States to treat the monoliths in order to recover the PGMs, a great percentage of monoliths is exported to Europe and South Africa for recycling, and a lesser amount is exported to Japan. There is presently no commercial-scale capacity in place domestically to recover cerium from the monoliths. Recycling of cerium or cerium compounds from the monoliths could help ensure against possible global supply shortages by increasing the amount that is available in the supply chain as well as the number and geographic distribution of the suppliers. It could also reduce the amount of material that goes into landfills.

关键词：汽车；催化转换器；铈元素

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Owing to the favorable ambiguity function properties and the increased deployment, mobile communications systems are useful for passive bistatic radar applications. Further, simultaneously using multiple illuminators in a multistatic configuration will improve the radar performance, providing spatial diversity and increased resolution. We compute modified Cram r-Rao lower bounds (MCRLB) for the target parameter (delay, Doppler) estimation error using universal mobile telecommunications system (UMTS) signals as illuminators of opportunity for passive multistatic radar systems. We consider both coherent and non-coherent processing modes. These expressions for MCRLB are an important performance metric in that they enable the selection of the optimal illuminators for estimation.

关键词：双基地雷达；天线波瓣；多普勒系统；多操作

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