Sedimentation and centrifugation equipment comprises devices used for liquid separation applications. It includes clarifiers, disk centrifuges, decanters, dissolved air flotation systems, and hydrocyclones that are used in the Processing industries for various purification applications. The Power, Water and Wastewater, Mining, and Food and Beverages industries are some of the major end-users using sedimentation and centrifugation equipment.

关键词：沉淀；离心设备；液体分离装置应用；加工工业；纯化应用

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The Asia-Pacific biotech industry enjoyed robust growth and a good performance in the first half of 2014, due to a rapid increase in the number of biotech capital firms and a substantial number of medical companies establishing their own investment firms.

关键词：生物技术；生物制药；亚太市场

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In living organisms, many processes are executed through tightly regulated networks of multi-component macromolecular complexes. Knowledge of structure and dynamics of such assemblies is essential to understanding their biological mechanisms. Solid-state NMR spectroscopy is a prime method for studying macromolecular assemblies, at atomic-level resolution, particularly in systems that are insoluble and lack long-range order. In this report, we review the contemporary magic-angle-spinning (MAS) NMR methods for investigation of proteins assemblies. We describe the progress in multidimensional correlation spectroscopy, recoupling, and decoupling techniques. We discuss emerging methods for recording spectra at MAS frequencies of 40 kHz and faster. We review techniques for sensitivity enhancement and fast data collection. We address isotopic labelling approaches to alleviate spectral congestion, facilitate assignments, and highlight specific intra- and intermolecular interactions. Finally, we present recent case studies on exciting and challenging systems, including assemblies of bacterio-phages and HIV-1 proteins, cytoskeleton-associated proteins, gas vesicles, type Ⅲ secretion system, and protein-RNA complexes.

关键词：蛋白质总成;固态核磁共振;魔角旋转;化学位移各向异性重新挂钩;偶极重新挂钩

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Regenerative medicine involves the usage of therapeutically-induced or laboratory-grown human tissue to treat injured or diseased cells, tissues, or organs. It focuses on repairing, replacing, or regenerating damaged cells and, thus, offers a paradigm shift in healthcare treatments. The three main technologies used in regenerative medicine are small molecules and biologics, cell therapy, and gene therapy. Small molecules and biologics help in the regeneration of diseased cells and tissues, cell therapy helps in treating or preventing a condition, while gene therapy helps in the correction of any defective gene in the body.

关键词：再生医学；治疗诱发；实验室培养；人体组织；小分子和 生物；细胞治疗；基因治疗

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Biosimilars are follow-on versions of biological medicines that are developed after the expiry of the patent protection on the original product. Biosimilar medicines have a mechanism of action that is similar to that of the original biological medicines. Though biosimilars have similarities to the innovator product, they are not an exact copy of the reference biopharmaceutical product. Currently, biosimilars are being incorporated into oncology treatment practices. The biosimilars used in oncology in the supportive care setting are known as oncology biosimilars.

关键词：生物仿制药；后续生物药品；专利保护；支持治疗

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Human growth hormone is a proteinaceous hormone consisting of 191 amino acid residues secreted by the anterior part of the pituitary gland. In children and adolescents, it promotes linear growth. However, in adults, the level of the hormone in the blood starts declining and it primarily performs anabolic functions. The growth-promoting activities of human growth hormone are primarily carried out through its interaction with IGF and constitute its indirect action. The direct activities of human growth hormone, carried out through its interaction with the human growth hormone receptor, include its metabolic and anti-insulin activities.

关键词：人生长激素；蛋白质激素；脑垂体；前部分泌；合成代谢

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miRNAs are single-stranded, small, non-coding RNA molecules that regulate gene expression at the translation level. They play a vital role in research, diagnostics, and therapeutics to study expression of genes and to control diseases by gene silencing. They interact with mRNA molecules and regulate expression of genes by mRNA cleavage, translational repression, and deadenylation. They are generally 17-27 nucleotides long and regulate post-transcriptional mRNA expression by binding to the 3’ untranslated region of the mRNA sequence, which results in translational suppression and gene silencing. miRNAs are involved in a wide range of biological processes, including apoptosis, cell cycle control, and several developmental processes such as stem cell differentiation, hypoxia, hematopoiesis, neurogenesis, insulin secretion, cardiac and skeletal muscle development, aging, cholesterol metabolism, viral replication, and immune responses. They can be used as therapeutics for the treatment of some severe diseases including cancer and genetic disorders by introducing specific miRNAs into diseased cells to silence the defective gene.

关键词：miRNA；单链；非编码RNA分子；调节；基因表达；研究；诊断；治疗

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Antisense and RNAi therapeutics are new innovative therapeutic options that can be used for the treatment of serious chronic and rare diseases. RNAi is an RNA-based gene silencing process in which RNA molecules inhibit gene expression by destroying specific mRNA molecules. Antisense technology involves the synthesis of a strand of nucleic acid that would bind to the disease-causing mRNA. It binds to the mRNA or to a splicing site on the pre-mRNA and inactivates it effectively. RNAi and antisense are two of the predominant technologies used by pharmaceutical companies, research institutes, and others for various applications in research, diagnostics, and therapeutics. RNAi therapeutics offers a wide scope in the treatment of diseases such as cancer and neurodegenerative diseases. Two types of RNA molecules are used in RNAi technology: miRNA and siRNA. RNAi molecules bind to other specific RNAs in the cell, such as mRNA, to manage their activity to treat the RNA-mediated disorder.

关键词：反义；RNAi疗法；创新；治疗选择；慢性疾病；罕见疾病

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报告从产业动态、产业分析、技术趋势、企业跟踪、地方动向等几个方面对生物科技产业进行了分析评论。

关键词：生物科技；生物制药；医疗器械；产业分析；技术趋势；企业跟踪；地方动向

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Biometrics is a technology that is used to identify, measure, and analyze the biological characteristics of an individual. Moreover, it is also used to analyze and validate individual characteristics such as DNA, fingerprints, iris, and hand geometry.

关键词：亚太地区；生物；测定学；统计学

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