中信证券研究部前瞻研究团队持续跟踪全球科技前沿。“全球科技产业”周报重点关注 中美科技互联网巨头变化，以及全球科技产业前沿动态。我们重点关注的科网巨头公司 包括：苹果、亚马逊、微软、谷歌、特斯拉、奈飞、英伟达、华为、腾讯、阿里、字节 跳动、小米、三星等。

2020 年 10 月 16 日，中共中央政治局就量子科技研究和应用前景举行第二十四 次集体学习。薛其坤院士就量子科技进行了汇报。习近平主席指出要找准我国量 子科技发展的切入点和突破口，统筹基础研究、前沿技术、工程技术研发，培育 量子通信等战略新兴产业，抢占量子科技国际竞争制高点，构筑发展新优势。

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Digital polymerase chain reaction (d-PCR) is considered a next-generation PCR technology offering rapid, sensitive quantification of nucleic acid when compared to the conventional PCR technology. Digital PCR is highly precise, where each sample partitioned into a number of individualized reactions or as droplets in a droplet-based digital PCR. These partitioned droplets are analyzed after a separate PCR reaction takes place per single sample, and the absolute number of molecules present in the sample is calculated. In the droplet digital PCR, the sample partitioning enables precise detection of single template molecules and specific quantification while mitigating the effects of target competition, reducing the PCR bias, and improving the sensitivity of the assays. Digital PCR offers significant benefits over other PCR methods and is considered a new approach to nucleic acid detection and quantification. Due to the absolute quantification of biological samples, this technique has found its application in various clinical areas, such as rare mutation detection, copy number variation, liquid biopsy, gene expression, miRNA analysis, single-cell analysis, pathogen detection, and next-generation sequencing (NGS) library analysis.

Biodegradable plastic is a plastic that decomposes naturally in the environment. This is mainly done by the microorganism present in the environment that breaks down the structure of biodegradable plastic. It is manufactured by micro-organism, renewable raw material, and petrochemicals. Biodegradable plastic is eco-friendly and has no toxicity as it is produced using renewable raw material. This type of plastic is mainly produced using natural plant material, which mainly includes corn oil, orange peels, starch, and plants. The report on biodegradable plastic exclusively focuses on current market trends and future growth opportunities of various types of biodegradable plastic such as polylactic Acid (PLA), Polybutylene adipate terephthalate ((PBAT), Polybutylene Succinate (PBS), Polyhydroxyalkanoates (PHA), Starch Blends, and others. On the basis of application, the market is divided into packaging, agriculture, textile, consumer durable, and others. Based on region, it is studied across North America, Europe, Asia-Pacific, and LAMEA.

The global cell & gene therapy market is one of the fastest-growing segments of the global regenerative medicine market. The market is growing at a healthy rate and this trend is expected to continue during the forecast period. This surge can be attributable to the growing prevalence of various chronic diseases like cancer, cartilage related problems, wounds, diabetic foot ulcer, genetic diseases, and other rare diseases across the globe. For instance, the prevalence of cancer and diabetes is increasing among the global population, and the medical solutions through conventional treatment methods are limited. There is a large unmet need in the treatments available today, and this need is fulfilled by cell & gene therapies. The market is witnessing steady growth due to the increased availability of funding from various public and private institutes. In addition, there is increased support from the regulatory bodies for product approvals and providing fast-track designations to the products, which encourages vendors to manufacture the products at a faster rate. In addition, the government in various major nations is creating awareness about the cell & gene therapy among the population and bringing various strategies to facilitate affordability and payments for these treatments.

DNA damage leads to the incorporation and accumulation of aberrations and defects in the genome, which results in potential mutations. The occurrence of mutations in genes having vital proteins or enzymes leads to the development of cancer. However, the biological system is equipped with an effective repair mechanism capable of repairing the damaged DNA sequences in the cells. DNA damage response (DDR) drugs are used as a therapeutic strategy for augmenting the innate DNA repair mechanism, thereby aiding advanced cancer treatments. The development of DDR drugs potentially harnesses proteins involved in the DDR pathway such as Poly (ADP-ribose) polymerase (PARP), WEE1, Aurora B, ATM kinase, and ATR kinase.

DNA methylation is a heritable epigenetic marker which involves the covalent transfer of a methyl group to the C-5 position of the cytosine ring of DNA by enzymes known as DNA methyltransferases (DNMTs). In humans, DNA methylation occurs primarily at cytosines in any context of the genome. More than 98% of DNA methylation occurs in a CpG dinucleotide context in somatic cells. The current study aims to assess the global DNA methylation market by focusing on evaluating products catering to the aforementioned definition. The current scenario of DNA methylation detection and diagnosis is mainly dominated by several diagnostic majors, such as Illumina, Inc., Thermo Fisher Scientific Inc., Merck Group, and QIAGEN N.V., which offer a wide variety of products ranging from molecular-genetic tests to sequencing instruments for the confirmatory detection and diagnosis of DNA methylation. These products are generally based on technologies, such as polymerase chain reaction (PCR), microarrays, and sequencing, including both traditional and next-generation sequencing. The underlying utility of diagnostic testing for DNA methylation is based on the identification of clinically actionable genetic function, which provide crucial information on diagnosis, prognosis, and theranostics of genetic disorders and thereby facilitates clinical work-up, treatment management, and therapeutic selection.