Based on the research of the CAN/LIN bus communication protocol,an automobile lamps diagnostic system based on the CAN/LIN bus is designed.After the completion of the software and hardware designs of CAN nodes,LIN nodes and CAN/LIN nodes,the faults of automobile lamps can be successfully diagnosed.LIN node collects light switches and the gateway controls the car light's status via detecting the data frame on the LIN bus.The design and complementation of CAN node,LIN node and CAN/LIN gateway was finished,which made it possible to detect failures in vehicle.

关键词：汽车；灯光；故障诊断

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The VA Office of Inspector General (OIG) Office of Healthcare Inspections conducted a review in response to an allegation that a patient of the Amarillo VA Health Care System, Amarillo, TX (system) received negligent care resulting in permanent kidney damage, which in turn, led to multiple other medical problems. The purpose of the review was to determine whether the allegation had merit.

关键词：保健；检查；预防医学；肾疾病；医药

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The projects in this proposal specifically target several signal transduction pathways known to be critical for NSCLC p athogenesis including the EGFR pathway and the more downstream ras/raf/Mek/ERK pathway.

关键词：肺癌；标记；分子；死亡率；医药

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This guidance is intended to alert manufacturers of active pharmaceutical ingredients (APIs), pharmaceutical and medical device manufacturers of finished products, repackers, and others to the potential risk of crude heparin contamination. This guidance provides recommendations that will help API manufacturers, pharmaceutical and medical device manufacturers of finished products, repackers, and others, to better prevent the use of crude heparin that might contain over-sulfated chondroitin sulfate (OSCS) or non-porcine ruminant material contaminants.

关键词：肝素；污染；抗凝剂；预防医学；医药

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Steroid Receptor Coactivator-3 (SRC-3) is a transcriptional coactivator that promotes proliferation of prostate cancer (CaP) cells.

关键词：前列腺癌的细胞（生物学）；类固醇；医药

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The VA Office of Inspector General Office of Healthcare Inspections conducted a review to assess how Veterans Health Administration (VHA) medical facilities manage prevention of Legionnaires Disease (LD) at the request of the VA Secretary, Senator Robert P. Casey, Jr., Congressman Tim Murphy, and the Chairmen and Ranking Members of the House Committee on Veterans Affairs and the Senate Committee on Veterans Affairs.

关键词：保健检查；感染性疾病；预防医学；医药

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With estimated 232,340 new cases in 2013, breast cancer continues to be the most frequently diagnosed non-skin cancer among American women.

关键词：乳腺癌；肥胖；茶；血清中高密度；医药

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No abstract available.

关键词：气溶胶；哮喘；决策支持系统；医药

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The purpose of this work is to better understand the mechanisms of resistance to androgen biosynthesis inhibitors in men with castration resistant prostate cancer, and to investigate clinical methods of overcoming resistance.

关键词：前列腺癌；乙酸酯；雄激素；医药

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Recent data indicate that castration-recurrent prostate cancer (CR- CaP) progression is driven by the activation of wild-type androgen receptor (AR) through at least two mechanisms: tyrosine phosphorylation by Src family (SFK) and Ack1 tyrosine kinases, and the induction of AR coregulators that regulate the transcriptional activity of AR. It is likely that identifying novel AR-regulated genes in CR-CaP, especially those involving promoters with novel target sequences, will help elucidate the molecular mechanisms that drive CR-CaP initiation and progression, and will help identify potential new therapeutic targets for CRCaP. We propose to use ChIP-seq, exome-seq and bioinformatics analyses to comprehensively identify AR-regulated genes that drive the growth of human CR-CaP tumors in mice. The longterm aim of this work is to develop a CR-CaP progression gene signature, to identify CR-CaPassociated AR binding site motifs, and to identify potential new therapeutic targets in CRCaP.

关键词：雄激素；前列腺癌；受体位点（生理学）；医药

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