近期基因测序行业审评审批进展较多，世和基因国内首个NGS 大Panel 通过创新医疗器械特别审查、燃石医学国内首款多癌种 早检产品进入创新通道。伴随诊断是目前NGS 在肿瘤领域最主 要应用场景，此前海外已有多款大Panel 获批，后续国内更多企 业申报NGS 大Panel 以及行业标准的逐步完善值得期待。基于 NGS 的肿瘤早筛潜力巨大，目前海外代表产品Galleri 也尚未获 批，我们认为后续应关注技术指标进一步优化及更大人群数据的 读出。相关产品获批有望带来基因测序行业高速增长，行业创新进展值得关注。

多肽产业链：多肽产业链可分为以多肽创新药、多肽仿制药及多肽化妆品为主的下 游，以仿制药原料药、多肽CDMO 及美容肽原料公司为主的中游以及多肽合成试剂、 固相载体树脂、填料、固相合成仪为主的上游。 多肽发展历程：多肽合成技术的迭代，给药方式突破及适应症拓展推动了行业的发 展。多肽产业链经历了从1922 年首个多肽药物问世→固相合成法普及→多肽口服 制剂诞生→GLP-1R 激动剂多适应症开拓的发展，无论是供给端合成技术或给药方 式的突破，还是需求端新适应症的拓展，每次突破都推动了行业快速发展。当前随 着重磅多肽药物司美格鲁肽、替尔泊肽的高速放量，心衰、慢性肾病、NASH 等适 应症的持续开拓，新型多靶点多肽减重药物的不断研发，我们预计多肽产业链有望 迎来新一轮快速增长期。

GLP-1减重药物是目前医药第一热点，也是吸取全市场关注核心焦点，海外企业诺和诺德与礼来 制药市场的应用拓展全球领先，其适应症拓展和销售业绩指引让市场不断提高GLP-1的峰值预期， 国内企业作为跟随者或者原料试剂供应商也共同获益于市场的扩大。

Predictive analytics can be described as a branch of advanced analytics used to make predictions about unknown future events and activities that lead to decision-making. Predictive analytics in healthcare means helping healthcare professionals make more effective and efficient operational and clinical decisions, predict trends, and even find ways to control the spread of disease. This refers to the analysis of current and historical health data that enables.

Fraud is defined as a deliberate and dishonest act committed with the knowledge that it may result in an unauthorized benefit to the person who committed the act or to others who are similarly ineligible to benefit. Healthcare fraud is a type of fraud. Provider fraud is one of the biggest problems that Medicare is currently facing. Healthcare fraud is an organized crime that involves peers of providers, physicians, and beneficiaries acting together to make fraud claims. According to US legislation, an insurance company should pay a legitimate healthcare claim within 30 days. Thus, there is very little time to investigate the situation properly. Insurance companies are the most vulnerable institutions impacted due to these bad practices. According to the US government, the total Medicare spending increased exponentially due to fraud in Medicare claims.

Temperature-controlled logistics plays an instrumental role in the transportation of temperature-sensitive products in the healthcare sector, such as pharmaceutical products, bio-products, and equipment. Most pharmaceutical products require a temperature-controlled environment during the stage of manufacturing and distribution, which helps in maintaining the quality and effectiveness of pharmaceuticals. Consequently, pharmaceutical companies rely on temperaturecontrolled transportation and cold storage systems. Ineffective cold logistics management tends to result in higher operating costs and delays due to equipment malfunction or breakdown. Additionally, poor handling, wrong practices, and insufficient paperwork tend to increase the cost of cold chain logistics and expose products to risk and companies to substantial losses.

It is a novel class of small molecules with the dual mechanism as estrogen receptor antagonist ( and degrader SERDs are a type of hormonal therapy used in the treatment of ER positive/HER 2 negative locally advanced or metastatic breast cancer They can be employed as monotherapy or in combination with other drugs SERDs are considered one of the most revolutionary cancer therapies due to their superior clinical profile and ease of administration impacting the quality of life of breast cancer patients positively

According to the American Academy of Pediatrics ( Pediatrics is the specialty of medical science that is concerned with the physical, mental, and social health of children from birth to adolescent stage Pediatrics comprises a broad spectrum of health services that range from preventive health care to the diagnosis along with the treatment of acute and chronic diseases

This procedure removes growths in the adrenal glands The adrenal glands are found on top of the kidneys and make hormones that are needed to help the body work properly Appendectomy • This procedure removes an infected appendix (the small finger like pouch at the end of the large intestine)

According to World Health Organization ( mental health is defined as a ‘state of well being in which an individual realizes his or her abilities, can cope with the normal stresses of life, can work productively, and can contribute to his or her community • Furthermore, according to MentalHealth gov (a sub division of the U S Department of Health Human Services), mental health comprises emotional, psychological, and social well being