关键词：医药；康复技术；儿童；自闭症谱系障碍；神经反馈

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The current proposal aims to explore the relationship between brain function and connectivity in selective pathways/circuits, neuropsychological functioning, and cognitive rehabilitation response in Veterans with both Traumatic Brain Injury (TBI) and Posttraumatic Stress Disorder (PTSD). Toward this end, we propose a randomized clinical trial involving a cognitive rehabilitation intervention that targets improved executive functioning, with the participation of N=100 Veterans diagnosed with both TBI and PTSD (n=50 experimental/n=50 control). We have just begun recruitment three months ago and enrolled n=15 dyads of veterans and family members at this point.

关键词：医药；康复技术；创伤后应激障碍；退伍军人；认知康复

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This study is a randomized trial of a hybrid treatment for Iraq and Afghanistan Veterans with a history of mild to moderate TBI (mTBI) and PTSD. Emotional symptoms are likely a main cause of the persistence of post- concussive symptoms while thinking problems and emotional control problems associated with mTBI can impede recovery from PTSD. However, there is no PTSD treatment specifically designed to accommodate the difficulties with attention, memory, and problem solving that patients with TBI may have. Therefore, this study integrates therapeutic approaches and tests a modification of cognitive processing therapy (CPT), an empirically supported treatment for PTSD, in which CPT is enhanced with compensatory cognitive rehabilitation principles. The enhanced CPT, called SMART-CPT is being compared to standard CPT in a group of Iraq and Afghanistan Veterans with a history of both mTBI and PTSD. Half of the participants are randomly assigned to receive standard CPT and half to receive SMART-CPT. This year was dedicated to study start up, including regulatory approvals and treatment manual development. Initial recruitment and enrollment of participants began in the final quarter of the year; six Veterans are currently enrolled and active in the protocol. There is no data to report at this time.

关键词：医药；康复技术；创伤后应激障碍；创伤性脑损伤；军事人员

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This report is based on research conducted by the Minnesota Evidence-based Practice Center (EPC) under contract to the Agency for Healthcare Research and Quality (AHRQ), Rockville, MD (Contract No. 290-2007-10064-I). The findings and conclusions in this document are those of the authors, who are responsible for its contents; the findings and conclusions do not necessarily represent the views of AHRQ. Therefore, no statement in this report should be construed as an official position of AHRQ or of the U.S. Department of Health and Human Services. The information in this report is intended to help health care decisionmakers--patients and clinicians, health system leaders, and policymakers, among othersmake well-informed decisions and thereby improve the quality of health care services. This report is not intended to be a substitute for the application of clinical judgment. Anyone who makes decisions concerning the provision of clinical care should consider this report in the same way as any medical reference and in conjunction with all other pertinent information, i.e., in the context of available resources and circumstances presented by individual patients.

关键词：医药；康复技术；脑创伤；医疗保健及竞争

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2014年3月5日，国务院总理李克强在人大开幕会议上作了政府工作报告，对2013年的工作做了回顾，并对2014年重点工作做了规划。我们对医药相关内容做一梳理和解读。

关键词：医药行业；政府工作报告

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关键词：儿童药；研究伦理；升级

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较快增长—1-8月份，医药制造业实现销售收入12723.6亿元，同比增长18.7%.商业贿赂—据中国医药企业管理协会副会长牛正乾介绍，从8月开始，此次反商业贿赂调查对行业的影响开始逐步显现，医药企业经营更加谨慎。并购热潮—今年以来医药上市公司的并购节奏明显加快，相关案例不下20个。中药颗粒—中药配方颗粒销售规模小、市场潜力大、主要生产企业均着手产能扩增。

关键词：医药行业；收入；利润；化学药品制；非处方药；原料药

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关键词：河南；基药；直采目录

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关键词：发改委；试点药品；价格改革

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Biosimilars are defined as the follow-on versions of original biological medicines. These are separately developed after the patent protecting the original product has expired. Biosimilar medicines are intended to have the same mechanism of action as original biological medicines, and are designed to treat the same diseases as the innovator’s product. However, biosimilars have many similarities, but are not identical to the reference biopharmaceutical product. This is mainly because the nature of the manufacturing process and the size and complexity of the active substances in biosimilars differ from the generic chemical products.

关键词：生物仿制药；生长激素；促红细胞生成素；白细胞介素；胰岛素

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