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20681.3-S-(β-D-吡喃葡萄糖基)-1,2,4-三唑的合成及抗菌活性
[化学原料和化学制品制造业] [2015-10-05]
以自制的5-取代芳基-4-氨基-3-巯基-1,2,4三唑为底物,经糖基修饰后,在甲醇钠/甲醇/二氯甲烷体系中经水解脱除糖环上的乙酰基,得到9个新化合物5-取代苯基-4-氨基-3-S-(β-D-吡喃葡萄糖基)-1,2,4-三唑(6a~6i),其结构经核磁共振波谱(1H NMR,13C NMR),红外光谱(IR)和高分辨质谱(HRMS)确认.生物活性测试结果表明,目标化合物对大肠杆菌、金黄色葡萄球菌、枯草芽孢杆菌和白色念珠菌均显示出良好的抑菌活性.化合物6g对大肠杆菌、金黄色葡萄球菌、枯草芽孢杆菌和白色念珠菌的最小抑菌浓度分别达到2,8,32和8μg/m L,抑菌效果接近或优于对照药物三氯生和氟康唑.利用Autodock程序研究了目标化合物(6a~6i)与大肠杆菌烯脂酰还原酶(FabⅠ)受体蛋白分子的相互作用和结合自由能变化规律.
关键词：1,2,4-三唑；S-β-D-糖苷；去乙酰化；抗菌活性；烯脂酰还原酶
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20682.B掺杂STW结构硅酸盐分子筛的合成与表征
[化学原料和化学制品制造业] [2015-10-05]
在浓溶胶体系中,以2-乙基-1,3,4-三甲基咪唑阳离子(2E134TMI)为模板剂,于175℃晶化合成了具有STW结构的B掺杂硅酸盐手性分子筛(B-STW),并对样品的结构、化学组成、晶相、形貌和酸性等性质进行表征.结果表明,B-STW具有弱酸性,热稳定性高,结构稳定温度达到750℃.
关键词：硼掺杂硅酸盐分子筛；硅酸盐手性分子筛结构；手性分子筛；浓溶胶合成；离子液体
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20683.基于表面增强拉曼散射的敌草快检测方法
[化学原料和化学制品制造业] [2015-10-05]
利用表面增强拉曼散射(SERS)技术,以银镜为SERS活性基底,建立了一种快速检测敌草快的分析方法.紫外光谱结果表明,敌草快分子在p H≤9的条件下可以稳定存在;在较宽的范围内(p H=1~9)p H值对SERS检测结果无影响.因此,无需对敌草快溶液的p H值进行调节即可进行SERS检测,简化了待测样品的预处理过程.SERS光谱检测结果表明,敌草快的特征峰强度随着浓度的降低而降低.该方法对敌草快的检测限可以达到10-8mol/L.此方法操作简单,检测速度快,能够实现对敌草快的无损检测分析.
关键词：表面增强拉曼散射光谱；1,1’-乙撑-2,2’-联吡啶二溴盐；敌草快；银镜；检测
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20684.5,5’-二硫代双(琥珀酰亚氨基-2-硝基苯甲酸)功能化的SERS纳米探针在免疫检验中的应用
[化学原料和化学制品制造业] [2015-10-05]
以5,5’-二硫代双(琥珀酰亚氨基-2-硝基苯甲酸)(DSNB)分子作为偶联剂将蛋白质结合在金纳米粒子表面,既保持了蛋白质的生物活性,同时DSNB分子又具有较高的表面增强拉曼散射(SERS)活性,可作为蛋白质定量分析的探针分子.选用生物素与亲和素的特异性识别以及抗原抗体的免疫识别2个生物反应体系,将SERS纳米探针固定在蛋白质检测芯片上.以硅片为蛋白质检测载体,利用硅片在520 cm-1处的拉曼特征峰为内标,对人Ig G抗体进行定量分析.结果表明,该探针对人Ig G抗体检测的最低浓度可以达到5 pg/m L.
关键词：表面增强拉曼散射；免疫检验；纳米探针；生物素；链霉亲和素
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20685.三嗪吡唑类配位超分子化合物的合成、结构及光催化活性
[化学原料和化学制品制造业] [2015-10-05]
在水和乙醇的混合体系中合成了2个配位化合物[Co(Bpz*ea T)(H2O)3]·2H2BTC·2H2O(1)和[Cu(Bpz*ea T)(H2O)3]·2H2BTC·CH3CH2OH·H2O(2)[Bpz*ea T=2,4-二(3,5-二甲基吡唑)-6-二乙胺基-1,3,5-三嗪;H3BTC=均苯三甲酸].通过元素分析、红外光谱、紫外光谱、热重分析、X射线粉末衍射以及X射线单晶衍射方法对配合物进行了表征.结构分析表明,配合物1和2的中心金属均为六配位,形成扭曲的八面体构型.通过分子间氢键的作用,配合物1和2分别被连接成三维和二维的超分子结构.此外,对2个配合物的光催化活性进行了研究.
关键词：钴/铜配合物；三嗪吡唑；超分子；晶体结构；光催化活性
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20686.超高容量氧化石墨烯/碳纳米管气凝胶用于血红蛋白的吸附分离
[化学原料和化学制品制造业] [2015-10-05]
采用冷冻干燥技术制备了三维氧化石墨烯/碳纳米管(GO/CNTs)气凝胶,在疏水作用下,该气凝胶对蛋白质表现出良好的吸附性能.在p H=8.0时,GO/CNTs气凝胶对血红蛋白的吸附效率很高,而对白蛋白基本不吸附,从而可实现血红蛋白的选择性吸附分离.在最佳吸附条件下,GO/CNTs气凝胶对血红蛋白的吸附容量高达3793.3 mg/g,是去除高丰度血红蛋白的高效材料.吸附后的血红蛋白可以使用p H=11.5的BrittonRobisin缓冲液有效洗脱,回收率为67%.圆二色光谱结果表明,GO/CNTs气凝胶具有良好的生物相容性,其表面发生的吸附/洗脱过程对血红蛋白的构象基本无影响.将GO/CNTs气凝胶用于人全血样品中血红蛋白的选择性分离,SDS-聚丙烯酰胺凝胶电泳结果表明得到了较高纯度的血红蛋白.
关键词：氧化石墨烯；碳纳米管；气凝胶；血红蛋白；分离
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20687.全球富马酸市场报告（2015-2019年）
[化学原料和化学制品制造业] [2015-09-24]
Fumaric acid, also known as trans-butenedioic acid, is a white crystalline compound found in nature. It is the primary intermediate in the tricarboxylic acid cycle for the biosynthesis of organic acid in humans and other mammals. Fumaric acid is used as a food additive. It provides long-lasting and steady sourness because of its hydrophobic character. It also enhances the flavor and improves the quality. Fumaric acid also reduces packaging material costs for dry mixes products because of its reduced moisture barrier requirements.
关键词：富马酸；反式丁烯二酸；三羧酸循环；生物合成；有机酸；食品添加剂；增强风味；提高质量
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20688.全球生物聚酰胺市场报告（2015-2019年）
[化学原料和化学制品制造业,科学研究和技术服务业] [2015-09-24]
Bio-based polyamides are in high demand as these are made from renewable and biobased feedstock. These materials are likely to exhibit a superior environmental profile and deliver applicative performances at a competitive price. All the major market players are aggressively pursuing agreements, M&A, and partnerships with other vendors to leverage the opportunity inherent in the market and build a competitive edge.
关键词：生物基聚酰胺；可再生能源；生物基发原料；应用性
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20689.全球地质聚合物市场报告（2015-2019年）
[化学原料和化学制品制造业] [2015-09-18]
Geopolymer is a mineral chemical compound or a mixture of compounds that consists of repeating units of compounds such as silico-aluminate (-Si-O-Al-O-), silico-oxide (-Si-O-Si-O-), alumino-phosphate (-Al-O-P-O-), or ferro-silico-aluminate (-Fe-O-Si-O-Al-O-). These mineral compounds are prepared by a process known as geopolymerization. Geopolymers can also be formed at room temperature using industrial waste or by-products produced during the manufacture of other compounds. They are similar to ordinary Portland cement. Geopolymer binder can easily replace (fully or partially) ordinary Portland cement as it has similar benefits. The main advantage of geopolymer binder over ordinary Portland cement is its low carbon dioxide emission, which is almost 80%-90% lower, which helps protect the environment.
关键词：地质聚合物；无机化学化合物；工业废料；副产物；矿物聚合粘合剂；保护环境
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20690.全球苯胺市场报告（2015-2019年）
[化学原料和化学制品制造业] [2015-09-18]
The market is expected to grow at a steady pace during the forecast period, driven by increased demand for polyurethane (PU) rigid foams. More than 80% of aniline is used to manufacture methylene diphenyl diisocyanate (MDI). MDI-based PU is increasingly used in the construction, plastic, and automotive industries. The increased consumption of aniline in the agriculture, insulation, consumer goods, transportation, adhesives, sealants, coatings, electronics, photography, pulp and paper, textiles, packaging, and pharmaceuticals industries is also boosting market growth.
关键词：苯胺；聚氨酯（PU）；亚甲基二苯基二异氰酸酯；稳健的步伐
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