This guide helps you get started with a typical installation for Oracle? Database? 11g Release 2 using a script package and defines the requirements of this automation in IBM? PureApplication? System.

关键词：PureApplication；IBM模式实验室；Oracle数据库

查看摘要 索取原文[14页]

This guide helps you get started with a typical run of the Windows? OS Preparation V1 Script Package and defines the requirements of this automation in IBM? PureApplication? System.

关键词：PureApplication；IBM模式实验室；Windows操作系统；脚本包V1

查看摘要 索取原文[14页]

In this two-article series, learn how to use Scalable Vector Graphics (SVG) with the open source D3 JavaScript library to create data visualizations. Shapes, colors, and layouts can be of great help in making business sense out of data volumes. An example scenario demonstrates the use of SVG and D3 for creating informative graphics out of browsing metrics for social media.

关键词：数据可视化；可视化浏览；SVG；D3指标

查看摘要 索取原文[23页]

Machine logs from diverse sources are generated in an enterprise in voluminous quantities. IBM? Accelerator for Machine Data Analytics simplifies the task of implementation required so analysis of semi-structured, unstructured or structured textual data is accelerated.

关键词：IBM加速器；加速机；数据分析

查看摘要 索取原文[31页]

Learn how to consume IBM InfoSphere BigInsights data through IBM Cognos Business Intelligence 10.2.

关键词：InfoSphere BigInsights ；商业智能报告；Cognos 10.2

查看摘要 索取原文[11页]

At Innovate 2013: The IBM Technical Summit, you'll receive the insights you need to stayahead of the major trends "re-innovating" system and software delivery throughout the DevOpscycle — cloud, mobile, social collaboration, big data, agile, and analytics. On a personal note,the insights you gain can help you stay ahead in your career goals through tech and businessknowledge from peers, IBM experts, and IBM clients. This article offers some developerWorkscloud resources to supplement your conference experience.

关键词：技术改变；团队路线；软件

查看摘要 索取原文[7页]

New to IBM InfoSphere Streams 2.0, the introduction of the metrics component provides runtime access to system and user-defined statistics than can be used to monitor the inner workings of your Streams application. This article outlines the new metrics system and describes how to access and use both system and user-defined metrics as part of your Streams application.

关键词：InfoSphere Streams 2.0；度量组件；Streams应用程序

查看摘要 索取原文[14页]

This article is focused on explaining Big Data and then providing simple worked examples in Hadoop, the major open-source player in the Big Data space. You'll be happy to hear that Hadoop is NOT a replacement for Informix or DB2, but in fact plays nicely with the existing infrastructure. There are multiple components in the Hadoop family and this article will drill down to specific code samples that show the capabilities. No Elephants will stampede if you try these examples on your own PC.

关键词：Hadoop；大数据；开源播放器；开源数据

查看摘要 索取原文[38页]

Tamoxifen, the first targeted therapy, has shown great success in treating estrogen receptor (ER) positive breast cancer. However, both acquired and de novo resistance to this therapy prevents it from being effective in all situations. Multiple lines of evidence indicate that increased signaling through growth factor pathways, such as the IGF pathway, mediates resistance to tamoxifen. The link between ER and ICGF1R leads us to hypothesize that IGF system crosstalk with the ER contributes to tamoxifen resistance. Tamoxifen resistance has thus provided researchers with a reason to investigate other growth factor pathways involved in breast cancer. As new targeted therapies are being developed, it will be important to examine their benefit with existing therapies. In order to examine the effectiveness of anti-IGF1R inhibitors in vitro, tamoxifen resistant (TamR) cells were generated by culturing MCF-7L and T47D cells in the presence of 4-OH-tamoxifen for >6 months. TamR cells had dimished levels of IGF1R, with unchanged levels of insulin receptor (IR). Further, TamR cells failed to respond to IGF-I induced p-AKT activation, while retaining responsiveness to both insulin and IGF-II. Additionally, IGF-I failed to enhance the proliferation and anchorage-independent growth of TamR cells; however, both insulin and IGF-II were able to enhance proliferation in MCF anchorage-independent growth. An IGF1R antibody was effective in inhibiting signaling, anchorage-independent growth, and proliferation in MCF-7L cells, but had no effect in TamR cells. In contract, an IGF1R/TR tyrosine kinase inhibitor was effective in both MCF-7L and TamR cells. In a xenograft model, an IGF1R antibody was able to inhibit estrogen stimulated tumor growth, but had no additive effect when combined with tamoxifen treatment. Further, tamoxifen-treated xenografts had diminished IGF1R levels.

关键词：医药；治疗技术；类胰岛素生长因子受体；抗雌激素受体

查看摘要 索取原文[33页]

The complete annual report for 1977 gives information on supported projects in the Program for Energy Research and Technologies, 1977--1980 of the Federal Government excluding projects relating to nuclear energy and fusion research; it is broken down into three subprograms: (1) efficient use of energy in application and in secondary energy; (2) coal and other fossil sources of primary energy; (3) new sources of energy. This document presents only subprogram (3), new sources of energy, as excerpted from the overall annual report, namely: development of new energy sources (solar energy, wind energy, geothermal energy) through ascertaining energy availability and its regional distribution; development of technologies for use and conversion; and demonstration of technical and economic feasibility. Ninety-four projects are described, including objectives, funding, and status. Additional information on the projects is included in appendix.

关键词：太阳能；新能源；地热能源；波浪发电

查看摘要 索取原文[311页]