Pulmonary arterial hypertension (PAH) is a life-threatening condition with a pulmonary vascular resistance that leads to elevated pulmonary arterial pressures, right ventricular failure, and ultimately death. PAH is high blood pressure in the arteries that carry blood from the heart to the lungs. It occurs when blood vessels become narrow,making the blood flow difficult. The heart must work harder to pump blood through those narrow arteries. This creates pressure on the heart’s right ventricles, which increase in size and become weaker due to the excess load, leading to heart failure.The global PAH drugs market is expected to benefit from the growing incidence of PH.This has driven the vendors to conduct extensive R&D activities, thereby driving the market growth.

PART 01: Executive summary 6

PART 02: Scope of the report 18

PART 03: Research Methodology 23

PART 04: Introduction 26

Key market highlights 26

PART 05: An overview of PAH 27

PART 06: Pipeline analysis 28

PART 07: Market landscape 30

Market overview 30

Five forces analysis 32

PART 08: Market segmentation by route of

administration (RoA) 33

Oral administration 33

Injectables 34

Inhalation 34

PART 09: Market segmentation by mechanism of action

(MoA) 35

ERAs 35

Prostacyclin analogs 36

PDE inhibitors 37

sGC stimulators 38

PART 10: Geographical segmentation 40

PAH market in Americas 41

PAH market in EMEA 43

PAH market in APAC 45

PART 11: Decision framework 47

PART 12: Drivers and challenges 49

Market drivers 50

Impact of drivers on key customer segments 52

Market challenges 53

Impact of challenges on key customer segments 55

PART 13: Market trends 56

Increased focus on combination therapies 56

Increase in awareness 56

Intense competition among vendors 57

PART 14: Vendor landscape 58

Competitive scenario 58

PART 15: Key vendor analysis 60

Actelion Pharmaceuticals 60

DAIICHI SANKYO 63

GlaxoSmithKline 65

Novartis 67

United Therapeutics 71

Other prominent vendors 73

PART 16: Appendix 77

List of abbreviations 77

PART 17: Explore Technavio 78