Structural analysis of the Fab Fragment of Monoclonal Antibody MN423
作者：Jozef Sevcik，Natalia Csokova，Rostislav Skrabana，Lubica Urbanikova，Michal Novak 作者单位：Institute of Molecular Biology, Slovak Academy of Sciences, Dubravska cesta 21, 845 51 Bratislava, Slovak Republic；Institute of Neuroimmunology, Slovak Academy of Sciences, Dubravska cesta 9, 845 10 B 加工时间：2013-12-21 信息来源：科技报告（Other） 索取原文[2 页]
关键词：单克隆抗体；片段；结构分析 摘 要：Monoclonal antibody (mAb) MN423 recognizes Alzheimer’s disease specific conformation of tauprotein assembled into paired helical filaments (PHF). Since the three-dimensional structure of PHF is currently unavailable, the structure of MN423 binding site could provide important information about PHF conformation.
索取原文[2 页]
027-87841330