关键词：miRNA；单链；非编码RNA分子；调节；基因表达；研究；诊断；治疗
摘 要：miRNAs are single-stranded, small, non-coding RNA molecules that regulate gene expression at the translation level. They play a vital role in research, diagnostics, and therapeutics to study expression of genes and to control diseases by gene silencing. They interact with mRNA molecules and regulate expression of genes by mRNA cleavage, translational repression, and deadenylation. They are generally 17-27 nucleotides long and regulate post-transcriptional mRNA expression by binding to the 3’ untranslated region of the mRNA sequence, which results in translational suppression and gene silencing. miRNAs are involved in a wide range of biological processes, including apoptosis, cell cycle control, and several developmental processes such as stem cell differentiation, hypoxia, hematopoiesis, neurogenesis, insulin secretion, cardiac and skeletal muscle development, aging, cholesterol metabolism, viral replication, and immune responses. They can be used as therapeutics for the treatment of some severe diseases including cancer and genetic disorders by introducing specific miRNAs into diseased cells to silence the defective gene.
目 录：

01. Executive Summary

02. List of Abbreviations

03. Scope of the Report

03.1 Market Overview

03.2 Product Offerings

04. Market Research Methodology

04.1 Market Research Process

04.2 Research Methodology

05. Introduction

06. Market Landscape

06.1 Market Overview

06.2 Market Size and Forecast

06.3 Five Forces Analysis

07. Market Segmentation by Application

07.1 Global miRNA Research Market

07.1.1 Market Size and Forecast

07.2 Global miRNA-based Diagnostics Market

07.2.1 Market Size and Forecast

07.3 Global miRNA-based Therapeutics Market

07.3.1 Pipeline Snapshot

08. Geographical Segmentation

08.1 miRNA Market in Americas

08.1.1 Market Size and Forecast

08.2 miRNA Market in EMEA Region

08.2.1 Market Size and Forecast

08.3 miRNA Market in APAC Region

08.3.1 Market Size and Forecast

09. Buying Criteria

10. Market Growth Drivers

11. Drivers and their Impact

12. Market Challenges

13. Impact of Drivers and Challenges

14. Market Trends

15. Trends and their Impact

16. Vendor Landscape

16.1 Competitive Scenario

16.1.1 Key News

16.1.2 Mergers and Acquisitions

16.2 Vendor Analysis 2013

16.3 Other Prominent Vendors

17. Key Vendor Analysis

17.1 Affymetrix

17.1.1 Key Facts

17.1.2 Business Overview

17.1.3 Business Segmentation

17.1.4 Business Segmentation by Revenue 2013

17.1.5 Business Segmentation by Revenue 2012 and 2013

17.1.6 Sales by Geography

17.1.7 Business Strategy

17.1.8 Key Information

17.1.9 SWOT Analysis

17.2 Agilent Technologies

17.2.1 Key Facts

17.2.2 Business Overview

17.2.3 Business Segmentation by Revenue 2013

17.2.4 Business Segmentation by Revenue 2012 and 2013

17.2.5 Geographical Segmentation by Revenue 2013

17.2.6 Business Strategy

17.2.7 Recent Developments

17.2.8 SWOT Analysis

17.3 Exiqon

17.3.1 Key Facts

17.3.2 Business Overview

17.3.3 Business Segmentation by Revenue 2013

17.3.4 Business Segmentation by Revenue 2012 and 2013

17.3.5 Geographical Segmentation by Revenue 2013

17.3.6 Business Strategy

17.3.7 Recent Developments

17.3.8 SWOT Analysis

17.4 Qiagen

17.4.1 Key Facts

17.4.2 Business Overview

17.4.3 Product Segmentation by Revenue 2013

17.4.4 Product Segmentation by Revenue 2012 and 2013

17.4.5 Geographical Segmentation by Revenue 2013

17.4.6 Business Strategy

17.4.7 Recent Developments

17.4.8 SWOT Analysis

17.5 Thermo Fisher Scientific

17.5.1 Key Facts

17.5.2 Business Overview

17.5.3 Business Segmentation

17.5.4 Product Segmentation by Revenue

17.5.5 Sales Segmentation

17.5.6 Business Strategy

17.5.7 Key Information

17.5.8 SWOT Analysis

18. Other Reports in this Series