Tailored Approach to Prostate Cancer Therapy Based upon PTEN Status.
作者:Wachsberger, P. 作者单位:Thomas Jefferson Univ., Philadelphia, PA. 加工时间:2013-12-22 信息来源:科技报告(AD) 索取原文[22 页]
关键词:治疗;前列腺癌细胞;PTEN 摘 要:The purpose of this study was to investigate the hypothesis that PTEN null prostate cancer cells and tumors will exhibit increased radiosensitivity to inhibition of the DNA repair enzyme, PARP, compared to wild- type PTENexpressing cells and tumors, resulting in increased efficacy of radiotherapy and chemotherapy.