关键词：光谱成像；同心圆K-space轨道
摘 要：Purpose: To develop a robust and rapid imaging technique for hyperpolarized 13C MR Spectroscopic Imaging (MRSI) and investigate its performance. Methods: A concentric rings readout trajectory with constant angular velocity is proposed for hyperpolarized 13C spectroscopic imaging and its properties are analyzed. Quantitative analysis of design tradeoffs are presented for several imaging scenarios in terms of resolution, spectral bandwidth, acquisition time and SNR efficiency. Analysis comparing parallel imaging accelerated Cartesian sampling and concentric rings in terms of reconstruction noise amplification are also presented. Finally, the first application on 13C phantoms and in vivo animal hyperpolarized 13C MRSI studies were performed to demonstrate the feasibility of the proposed method. results: The concentric rings MRSI trajectory has the advantages of acquisition timesaving compared to echo-planar spectroscopic imaging (EPSI), and robustness to system timing delay and eddy currents compared to spiral MRSI. It provides a sufficient spectral bandwidth with a relatively high SNR efficiency compared to EPSI and spiral techniques. It will also be beneficial for parallel imaging by reducing noise amplificiation. Conclusion: The concentric rings trajectory is a robust and rapid imaging technique that fits very well with the speed, bandwidth, and resolution requirements of hyperpolarized 13C MRSI.