Stem cell therapy is the use of stem cells for the treatment or prevention of a disease or condition. Bone marrow transplant is the widely used stem cell therapy, followed by therapies derived from umbilical cord blood. Research is being undertaken to develop various sources (such as cord blood cells, bone marrow, and skin) for stem cells, and to apply them to various disorders like neurodegenerative diseases and conditions such as heart disease, diabetes, and other conditions.Stem cell therapy has become controversial after development in isolating and culturing of embryonic stem cells. This technique is used to create stem cells using somatic cell nuclear transfer and to create induced pluripotent stem cells (iPSCs). This controversy is related to abortion politics and human cloning. However, the changing regulatory landscape in several countries such as the US and Japan may help accelerate the clinical trials.

PART 01: Executive summary 7

PART 02: Scope of the report 19

PART 03: Research Methodology 24

PART 04: Introduction 27

Key market highlights 27

PART 05: Understanding of stem cell therapy 28

History of stem cell research 28

PART 06: Ethical issues and regulatory landscape 29

Ethical issues of stem cell research at different phases of

research 29

PART 07: Key clinical trials 33

Attractive clinical trial locations to invest 36

Commercially attractive therapy areas to invest 37

PART 08: Market landscape 48

Market overview 48

Five forces analysis 52

PART 09: Market segmentation by therapy 53

Allogeneic stem cell therapy 53

Autologous stem cell therapy 56

PART 10: Market segmentation by applications 59

Dermatology 59

Musculoskeletal 60

Cardiovascular 61

PART 11: Geographical segmentation 63

Stem cell therapy market in Americas 64

Stem cell therapy market in EMEA 67

Stem cell therapy market in APAC 69

PART 12: Market drivers 73

Limitations in traditional organ transplantations fueling

the demand for stem cell therapies 73

Increase in federal funding in stem cell therapy 73

Growing demand for personalized medicine 76

Increasing demand to develop effective drugs for

cardiology and degenerative disorders 77

PART 13: Impact of drivers 78

PART 14: Market challenges 79

Stringent regulatory environment affecting the product

approvals 79

Critical ethical challenges with respect to stem cell

research 80

High cost of clinical trials and failure rate in clinical

trials 80

PART 15: Impact of drivers and challenges 81

PART 16: Market trends 82

Evolution of new destinations in the development of stem

cell therapies 82

Increasing inorganic growth strategies such as

acquisitions and licensing agreements 83

Growing focus on the development of drugs for emerging

applications 85

Increasing investments from private enterprises likely to

fuel market growth 86

PART 17: Vendor landscape 87

Competitive scenario 87

PART 18: Key vendor analysis 92

Holostem Advanced Therapies 92

JCR Pharmaceuticals 94

Organogenesis 96

Osiris Therapeutics 99

Vericel 101

Other prominent vendors 104

PART 19: Appendix 117

List of abbreviations 117

PART 20: Explore Technavio 119