关键词:磁共振波谱成像;13C核磁共振;k空间;CRT
摘 要:Methods:A concentric rings readout trajectory with constant angular velocity is proposed for hyperpolarized 13C spectroscopic imaging and its properties are analyzed. Quantitative analysis of design tradeoffs are presented for several imaging scenarios in terms of resolution, spectral bandwidth, acquisition time and SNR efficiency. Analysis comparing parallel imaging accelerated Cartesian sampling and concentric rings in terms of reconstruction noise amplification are also presented. Finally, the first application on 13C phantoms and in vivo animal hyperpolarized 13C MRSI studies were performed to demonstrate the feasibility of the proposed method.Results:The concentric rings MRSI trajectory has the advantages of acquisition timesaving compared to echo-planar spectroscopic imaging (EPSI), and robustness to system timing delay and eddy currents compared to spiral MRSI. It provides a sufficient spectral bandwidth with a relatively high SNR efficiency compared to EPSI and spiral techniques. It will also be beneficial for parallel imaging by reducing noise amplificiation.