关键词：基因组；变异； 马尔科夫链蒙特卡罗；序贯重要性采样；粒子滤波
摘 要：We develop a method using reversible jump MCMC to infer genome-wide variable recombination rates and apply it to data from two Drosophila melanogaster populations. In addition, we describe a particle filtering method to sample genealogies from the posterior distribution.