关键词：胃肠道系统；精神障碍；活组织检查
摘 要：The goal of this project is to analyze the entire microbial population of the mucosa in the upper gastrointestinal tract of children with autism to determine if there is an overgrowth of specific populations of bacteria and analyze the relationship between the intestinal flora and behavior. Our current sub-contractor from the institute of Genome Sciences, University of Maryland School of Medicine was not able to amplify and sequence DNA from the duodenal biopsies of autistic children and controls. A new sub-contractor the Research and Testing Laboratory was found. A new set of duodenal biopsies from children with and without autism will be sent to the Research and Testing Laboratory for DNA extraction, PCR for 16S rRNA, sequencing. No additional funding will be requested to complete this project.