关键词：假肢；人脑控制；神经假体
摘 要：Brain-controlled prostheses have the potential to improve the quality of life of a large number of paralyzed persons by allowing them to control prosthetic limbs simply by thought.An essential requirement for natural use of such neural prostheses is that the user should be provided with somatosensory feedback from the artificial limb. This can be achieved by electrically stimulating small populations of neurons in the cortex; a process known as cortical microstimulation. This dissertation describes the development of novel technologies for experimental neuroscience and their use to explore the neural and perceptual effects of cortical microstimulation in rodents.