Over the past few decades, the pharmaceutical packaging panorama has seen a lot of changes and transformations. The launch of new technologies has lined the way for pharma packaging companies to discover more advanced solutions, enhance their procedures, and drive proficiencies across the supply chain. In the early days, glass medical and drug bottles were common and less costly to manufacture. However, plastic bottles were effective but very costly to produce on a mass scale.

Ultrapure water (UPW) is a highly purified water that has been purified to uncommonly stringent specifications. It is used as a cleaning agent in semiconductor plants. Therefore, the most important factor is that the water is treated to the highest levels of purity for all contaminants. The water should not contain any dissolved impurities that might settle on circuits, thereby leading to the failure of microchips. Hence, the growing applications in the semiconductor industry, especially in APAC and North America, are expected to accelerate the demand for ultrapure water during the forecast period.

With electrification being the way forward, OEMs will need to invest in dedicated platforms or start exploring options such as licensing to address the increasing and evolving needs of consumers. Autonomous driving requires a high level of electrical redundancy and drive-by-wire integration, which is possible through ECMs. ECMs offer OEMs the flexibility to make efficient use of available space and focus their efforts on designing the top hats, cutting down the lead time for new models.

Epigenetics modification, including histone modification, DNA methylation, and RNA-mediated processes modification, are key to impact gene expression primarily at the level of transcription; disturbing any of three marks that contribute to epigenetic modification can cause abnormal activation or silencing of genes. However, other steps in the process (for example, translation) may also be regulated epigenetically. The current study aims to assess the global epigenetics market by focusing on products (consumables, instruments, software) catering to end users, including pharmaceutical and biotechnology companies, academic and research institutions, contract research organizations (CROs), and other end users. The current market for epigenetics is majorly dominated by manufacturers and service providers such as Thermo Fisher Scientific Inc, Illumina, Inc, Bio-Rad Laboratories, Inc, PerkinElmer Inc, Agilent Technologies, Inc, F. Hoffmann-La Roche Ltd., Exact Sciences Corporation, Merck Group, Abcam plc., MDxHealth, Pacific Biosciences of California, Inc, QIAGEN N.V., Zymo Research Corporation, Active Motif, and Promega Corporation among others.

Medical grade tubing is a product designed for a number of applications that enable clinicians to perform several tasks, which normally include disposable applications such as medical catheters, IV sets, irrigation, drainage, and intravenous (IV) delivery. The applications are considered for medical applications such as abrasion protection, drug delivery, bulk disposable tubing, catheters, special applications, and other applications such as arthroscopy, endoscopy, and laparoscopy.

Diagnostics is an integral part of medical decision-making -- aid in acquiring information for a wide range of treatment dissemination, accentuating their criticality in healthcare. Molecular diagnostics has a critical role in precision medicine approach, as it ensures safe and effective application of targeted therapeutics. A majority of the players in the global molecular diagnostics market offer products encompassing the kits and reagents, instruments, and software categories. Also, several diagnostics and pharmaceutical companies are working collaboratively to develop NGS, PCR, IHC, ISH, microarray, nucleic acid amplification-, or mass spectrometry-based molecular diagnostics for the applications in several disease indications in order to enable efficient diagnosis, treatment selection, dosage selection, and treatment monitoring. Applications of molecular diagnostics primarily include infectious diseases, cancer, genetic testing, and women’s health, among others.

Biomanufacturing is the process of production of commercially important biomolecules by utilizing biological systems for use in medicines, food and beverage processing, and industrial applications. Natural sources such as blood, cultures of microbes, animal cells, or plant cells are often employed to carry out biomanufacturing. Cells used in the production process can also be derived using genetic engineering techniques.

On January 8, 2020, a pathogen of severe unexplained viral pneumonia was identified by sequencing and tentatively named the novel (new) coronavirus 2019 (2019-nCoV). On February 12, 2020, the International Committee on Taxonomy of Viruses officially named 2019-n CoV as SARS-CoV-2. On the same day, WHO officially named the disease coronavirus disease 2019 (COVID-19). Till now, about 4.18 million cases have been confirmed in 211 countries and territories such as the US and Southeast Asia, including severe and instances of death.

Over the last few years, the global pharmaceutical industry has undergone significant changes. In recent years, the cost of drugs has been increasing rapidly, a majority of which is contributed by funds allocated to research and development. According to a report published by Congressional Budget Office (CBO) in April 2021, titled, ‘Research and Development in the Pharmaceutical Industry,’ the U.S. pharmaceutical industry’s R&D expenditure in 2019 was nearly $83 billion, spanning a range of activities such as drug discovery, conducting clinical tests, and drug innovation, among others. Additionally, the report also states that the budget share allocated by pharmaceutical companies toward research and development has also increased. The following table shows a rough estimate of the annual R&D expenditure of pharmaceutical companies.

Preimplantation Genetic Testing: According to National Center for Biotechnology Information (NCBI), preimplantation genetic testing is defined as the testing of oocytes or embryos at the preimplantation stage for genetic defects. The technique is majorly performed in conjunction with in-vitro fertilization to minimize the risk of passing down inherited conditions. The respective genetic test is performed in the cases where there is a higher risk of passing on the inherited conditions. Some of the common conditions such as single gene diseases, chromosomal rearrangements, and aneuploidies, with the help of techniques such as fluorescence in situ hybridization (FISH), microarray, and next generation sequencing (NGS).