Peptoids are biomimetic polymers that combine the properties of proteins and plastics. This class of materials is predicted to play a significant role in several bio-electronic applications such as biosensors, drug discovery, and biomolecular recognition. In order to realize such potential, films of peptoids must first be reliably produced or transferred onto substrates of interest. This work reports the production of thin films of peptoids by way of various methods, including Gibbs monolayers, Layerby- Layer multilayers, and peptoid nanosheet (bilayer) formation. Gibbs films were successfully transferred onto silanized silicon substrates using the Langmuir-Schaefer technique as verified by X-ray Photoelectron Spectroscopy and Atomic Force Microscopy. Gibbs films were also prepared from a peptoid-peptide hybrid polymer, containing a peptide sequence specifically recognized and phosphorylated by the enzyme Casein Kinase II (CK2). An Ion-Sensitive Field-Effect Transistor containing this peptoid-peptide hybrid film is being fabricated as a biosensor for detecting CK2 activity.

关键词：类肽薄膜；生物传感器；潜在使用；医疗器械；生物电子；生物分子识别

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In this project, we propose to research the methodology for constructing adaptive computer-aided education systems for mammography. Improved mammography education could lead to improved benefit of mammography to breast cancer care and in turn to decreased mortality from the disease. The project includes: Observer studies to collect reading data from radiology trainees; Extraction of image features (human- and computer- based); Statistical modeling of the reader data to discover patterns in their error making; Development of methodology for adaptive training that utilizes the constructed models. The proposed adaptive system could improve education in mammography. This may in turn result in improved benefit of mammography in breast cancer detection and lower mortality associated the disease.

关键词：电子信息；计算机；钼靶训练；乳腺癌

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The paper presents a prototype of a system which can be used as a therapeutic and educational tool for children with developmental problems. Natural body movements and gestures are used in the system to interact with virtual objects displayed on the screen. Nowadays such systems can be built with the use of widely available free software tools for both graphical and vision applications. Such tools are also shortly presented in the paper.

关键词：电子信息；计算机；交互式系统；构建

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