Around 4%-6% of the global population is affected by lower back pain, and also the number of spondylolisthesis cases in gymnasts, weight lifters, and football linesmen and women is on the rise. Surgeons estimate that one in 10 individuals suffering from spine disorders

require surgery. In the US, about 450,000 spinal fusion procedures were performed in 2015, which corresponds to about 0.13% of the

US population. The average cost of lumbar spine fusion procedure is about $34,500. Total spine fusion procedures generated about $15.3

billion in the US in 2015. It was estimated that about 84% of the bone grafts are used in spine surgeries (spinal fusion procedures) to relieve back and neck pain. This rise in the number of spinal fusion surgeries will result in increased sales of lumbar spine fusion devices.

PART 01: Executive summary 7

Highlights 7

PART 02: Scope of the report 9

Top-vendor offerings 10

PART 03: Market research methodology 14

Research methodology 14

Economic indicators 14

PART 04: Introduction 15

Key market highlights 15

Lumbar fusion: An overview 16

PART 05: Market landscape 26

Market overview 26

Market size and forecast 29

Five forces analysis 32

PART 06: Market segmentation by product type 33

Implants and instrumentation 33

Biomaterials 34

PART 07: Global lumbar spine implants and

instrumentation market 37

Market overview 37

Market size and forecast 38

PART 08: Global lumbar spine fusion biomaterials

market 39

Market overview 39

Market size and forecast 41

PART 09: Market segmentation by procedure 44

Global lumbar spine fusion market by traditional

surgery 44

Global lumbar spine fusion market by minimally invasive

surgery 45

PART 10: Market segmentation by end-user 49

Hospitals 49

ASCs 49

PART 11: Geographical segmentation 51

Lumbar spine fusion market in Americas 52

Lumbar spine fusion market in EMEA 57

Lumbar spine fusion market in APAC 61

PART 12: Market drivers 64

Increase in prevalence of spinal disorders 64

Growing popularity of MI spinal surgeries 65

Rising popularity of physician-owned ASCs 66

PART 13: Impact of drivers 68

PART 14: Market challenges 69

Complications and risks associated with lumbar fusion 69

High cost of lumbar fusion surgery 69

Unfavorable reimbursement scenario 70

PART 15: Impact of drivers and challenges 71

PART 16: Market trends 72

Advances in technology 72

Rise in outsourcing by OEMs 72

Increase in M&A 73

Increased use of surface modified titanium in spinal

implants 75

PART 17: Vendor landscape 76

Competitive scenario 76

PART 18: Key vendor analysis 81

DePuy Synthes 81

Medtronic 84

NuVasive 87

Stryker 91

Zimmer Biomet 95

Other prominent vendors 100

PART 19: Appendix 102

List of abbreviations 102

PART 20: Explore Technavio 104