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再生医学的生物材料——壳聚糖和鱼胶原蛋白

Chitosan and Fish Collagen as Biomaterials for Regenerative Medicine
作者:Yoshihiko HayashiShizuka YamadaKajiro YanagiGuchiZenya KoyamaTakeshi lkeda 作者单位:Department of Cariology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan;Department of Cariology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Ja 加工时间:2013-12-14 信息来源:科技报告 索取原文[120 页]
关键词:生物医学;壳聚糖;胶原蛋白;再生医学;海洋产品
摘 要:This chapter focuses and reviews on the characteristics and bio medical application of chitosan and collagen from marine products and advantages and disadvantages of regeneration medicine. The understanding of the production processes of chitosan and colla gen and the conformation of these biomaterials are indispensable for promoting the theoretical and practical availability. The initial inflammatory reactions associated with chitosan application to hard and soft tissues need to be controlled before it can be considered for clinical application as scaffold. Further, as chitosan takes too long for biodegradation in vivo, generally it is not suitable for the scaffold for degenerative medicine in especially dental pulp tissue. The collagen extract from the scales of tropical fish has been reported to have a degeneration temperature of 35℃. The proper ties of biocompatibility and biodegradation of fish atelocollagen are suitable for the scaffold in regenerative medicine.
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