关键词:石墨烯;药物输送;癌症治疗
摘 要:The unique properties of graphene are attracting a significant amount of attention from scientists for various biomedical applications. Several attempts have been already made to functionalize the surface of graphene oxide with polymers, surfactants and other chemical moieties in an attempt to increase cellular uptake, to target a particular organ, in order to reduce the toxicity and/or to increase solubility. This review discusses various applications of graphene in biomedical sciences, their limitations and safety concerns. Literature reports confirm that almost 98% of study outcomes are promising, conducted either in vitro or in vivo. The dose dependent toxicity of graphene might serve as a tool to optimize formulation for effective delivery of a drug to particular site in the body. The applications of graphene in cell imaging and photodynamic therapy are being explored and can be associated with reduced chemotherapy. In order to gain a clear idea of bioclearance, real clinical data on graphene is essential for the future developments.