关键词：创伤性脑损伤；预算；临床医学；医药
摘 要：The current study involves a head to head comparison of the reliability and clinical validity of four neurocognitive assessment tools (NCAT s) for the acute neurocognitive assessment, tracking cognitive recovery, and informing clinical management after mild traumatic brain injury (mTBI). The specific NCAT s under study include: the Automated Neuropsychiatric Assessment Metric (ANAM), AXON Sports, Defense Automated Neurobehavioral Assessment (DANA), and Immediate Post-Concussion Assessment and Cognitive Testing (ImPACT). The study design involves both a Sports Concussion Arm and Civilian mTBI Arm. Both study arms are fully operational with data collection underway, with steady progress toward recruitment of mTBI/concussion participants and controls. In the first phase of data collection, we have enrolled more than 400 athletes in the baseline study phase, and 38 injured and control participants in the postinjury protocol. A new online e-consent platform developed as part of this project has been highly effective. Obstacles to recruitment in the civilian mTBI (hospital emergency dept.) arm have been identified and alternate strategies developed. Overall, the study is on target with respect to statement of work, timeline and budget. With ongoing recruitment of injured and control participants, we anticipate having informative data on our specific aims relevant to the NCAT s as part of future annual reports.