发改委网站10月12日消息，国家发改委发布《关于做好2013年天然气迎峰度冬工作的意见》，要求做好2013年天然气迎峰度冬工作。该意见认为，随着大气污染防治工作全面推进，各地用气需求超常规增长，今冬明春天然气供需矛盾较往年将更为突出，如遭遇持续低温等极端天气，保供形势将更加严峻。发改委要求，要继续完善价格机制。各地要抓紧出台天然气销售价格疏导方案和配套措施，争取冬季用气高峰前完成全部疏导工作，切实发挥价格杠杆调节供需的作用。同时，建立健全居民生活用气阶梯价格制度。具备条件的地区，可以在终端消费推行季节性差价和可中断气价等差别性价格政策，促进移峰填谷和节约用气，缓解天然气供应压力。

The Global Soft Contact Lens market is expected to grow at a steady pace during the period 2012-2016. The market was dominated by the Americas in 2012, and was followed by the APAC and EMEA regions. Factors such as ease of availability, presence of technologically-advanced soft lens materials, and the increasing adoption of the latest soft contact lens are expected to drive the growth of the Global Soft Contact Lens market during the forecast period. The market is expected to witness an improvement in its growth rate and post a CAGR of 5.94 percent during the period 2012-2016.

The purpose of this toxicological review is to provide scientific support and rationale for the hazard and dose-response assessment in IRIS pertaining to chronic exposure to tetrahydrofuran. It is not intended to be a comprehensive treatise on the chemical or toxicological nature of tetrahydrofuran. The intent of Section 6, Major Conclusions in the Characterization of Hazard and Dose Response, is to present the major conclusions reached in the derivation of the reference dose, reference concentration and cancer assessment, where applicable, and to characterize the overall confidence in the quantitative and qualitative aspects of hazard and dose response by addressing the quality of data and related uncertainties. The discussion is intended to convey the limitations of the assessment and to aid and guide the risk assessor in the ensuing steps of the risk assessment process.

Dioxins and dioxin-like compounds (DLCs), including polychlorinated dibenzo-dioxins, polychlorinated dibenzofurans, and polychlorinated biphenyls, are structurally and toxicologically related halogenated dicyclic aromatic hydrocarbons. Dioxins and DLCs are released into the environment from several industrial sources such as chemical manufacturing, combustion, and metal processing; from individual activities including the burning of household waste; and from natural processes such as forest fires. Dioxins and DLCs are widely distributed throughout the environment and typically occur as chemical mixtures. They do not readily degrade; therefore, levels persist in the environment, build up in the food chain, and accumulate in the tissues of animals. Human exposure to these compounds occurs primarily through the ingestion of contaminated foods (Lorber et al., 2009), although exposures to other environmental media and by other routes and pathways do occur. The health effects from exposures to dioxins and DLCs have been documented extensively in epidemiologic and toxicological studies. 2,3,7,8-Tetrachlor odibenzo-p-dioxin (TCDD) is one of the most toxic members of this class of compounds and has a robust toxicological database. Characterization of TCDD toxicity is critical to the risk assessment of mixtures of dioxins and DLCs because it has been selected repeatedly as the 'index chemical' for the dioxin toxicity equivalence factors (TEF) approach.

The purpose of this Toxicological Review is to provide scientific support and rationale for the hazard and dose-response assessment in IRIS pertaining to chronic exposure to tetrachloroethylene. It is not intended to be a comprehensive treatise on the chemical or toxicological nature of tetrachloroethylene.