糖尿病与体重管理药物市场需求广阔，GLP-1受体激动剂由于能促进胰岛素分泌并降低食欲控制体重，而且不容易引发低血糖等副作用，因此市场需求不断扩大。司美格鲁肽在降糖与减重方面效果较好，而且在慢性肾病、心血管病、非酒精性脂肪肝炎（Nash）等方面临床表现均较好，预计需求将继续增加。

23Q3全部公募基金占比12.49%，环比+0.79pp；剔除主动医药基金占比9.82%，环比+1.27pp；再剔除指数基金占比9.08%，环比+1.48pp；申万医药板块市值占比为7.59%，环比-0.12pp。从公募基金持仓家数来看，公募基金数量前五的分别是：恒瑞医药(545家)、药明康德(501家)、迈瑞医疗(443家)、智飞生物(224家)、爱尔眼科(195家) ；基金数量增加前五支股票分别是：药明康德(+283 家)、凯莱英(+75家)、百济神州-U(+63家)、康龙化成(+54家)、智飞生物(+53家)。

Sexual Lubricants, also known as lubes or personal lubricants, are a kind of gel, cream, fluid, or liquid that are used to reduce friction between the vagina & penis during sexual intercourse and reduces pain. Lubes are used to enhance the sexual experience and get more pleasure. Using sexual lubricants while sexual intercourse may be helpful for women experiencing vaginal dryness, & men who have erectile dysfunction. These are used widely for men, women, transgender, and LGBTQ+ community globally. They are used with condoms as well for additional comfort & ease and sometimes to reduce condom breakage. These lubricants are applied to the condom, penis, vagina, or rectum during sexual activity as it improves moistening. They are generally preferred by sex workers and men who have sex with men (MSM).

Self/home-based pregnancy test kits were the first rapid test kits under point-of-care (POC) diagnostics developed in 1976. The pregnancy test kit was developed in 1976. Pregnancy test kits are medical devices used to detect signs of pregnancy among women. The Human Chorionic Gonadotropin (hCG) hormone is considered a standard gold biomarker that provides overall information about pregnancy to identify the pregnancy. This hormone develops in the placenta during pregnancy. It helps to thicken the uterine lining, which supports to growth embryo and sends the signal to the body to stop menstruation. The level of hCG increase after conception and continue to increase until around ten weeks into pregnancy.

Infection control surveillance solutions are an integral component of healthcare systems that are designed to help prevent and control HAIs. These solutions range from comprehensive infection control systems that incorporate surveillance of pathogens, antimicrobial therapy management, infection prevention strategies, and antibiotic stewardship programs to more focused solutions that help track and monitor nosocomial and antimicrobial resistance (AMR) in a hospital setting. By recognizing the scope and prevalence of HAIs, infection control surveillance solutions help health professionals identify areas of potential concern and reduce the impact of infectious outbreaks.

Fraud is defined as a deliberate and dishonest act committed with the knowledge that it may result in an unauthorized benefit to the person who committed the act or to others who are similarly ineligible to benefit. Healthcare fraud is a type of fraud. Provider fraud is one of the biggest problems that Medicare is currently facing. Healthcare fraud is an organized crime that involves peers of providers, physicians, and beneficiaries acting together to make fraud claims. According to US legislation, an insurance company should pay a legitimate healthcare claim within 30 days. Thus, there is very little time to investigate the situation properly. Insurance companies are the most vulnerable institutions impacted due to these bad practices. According to the US government, the total Medicare spending increased exponentially due to fraud in Medicare claims.

Dermal fillers are injectable substances used to fill in wrinkles, facial lines, and depressions in the skin and add volume to areas of the face. Dermal fillers are used to treat many areas of the face, including the cheeks, lips, and skin around the eyes. The most common material used in dermal fillers is hyaluronic acid (HA), a naturally occurring substance in the body. Other fillers used include calcium hydroxylapatite (CaHA), Poly-L-Lactic acid (PLLA), and polymethylmethacrylate (PMMA). Dermal fillers are typically used in a series of treatments to achieve optimal results.

Sexual health supplements help improve potency during sexual activities, erectile dysfunction, infertility, and other conditions. They are consumed orally. Sexual health supplements are available in the market without a prescription and usually do not have any side effects on the human body. They are available in capsules, tablets, soft gels, liquids, and powders. Nutritional supplements are a part of the daily diet globally due to aging, lifestyle changes, and other factors. Common supplements include minerals, vitamins, and herbal products.

Temperature-controlled logistics plays an instrumental role in the transportation of temperature-sensitive products in the healthcare sector, such as pharmaceutical products, bio-products, and equipment. Most pharmaceutical products require a temperature-controlled environment during the stage of manufacturing and distribution, which helps in maintaining the quality and effectiveness of pharmaceuticals. Consequently, pharmaceutical companies rely on temperaturecontrolled transportation and cold storage systems. Ineffective cold logistics management tends to result in higher operating costs and delays due to equipment malfunction or breakdown. Additionally, poor handling, wrong practices, and insufficient paperwork tend to increase the cost of cold chain logistics and expose products to risk and companies to substantial losses.

Dietary fiber is an essential component of a healthy diet. It is usually found in fruits, vegetables, cereals, grains, legumes, nuts, and seeds. Foods containing fiber provide several health benefits, such as lowering the risk of diabetes, maintaining a healthy weight, heart diseases, constipation, and some types of cancer. These are commonly classified as soluble and insoluble fiber. The amount of insoluble and soluble fiber varies in different plant-based foods.

It is a novel class of small molecules with the dual mechanism as estrogen receptor antagonist ( and degrader SERDs are a type of hormonal therapy used in the treatment of ER positive/HER 2 negative locally advanced or metastatic breast cancer They can be employed as monotherapy or in combination with other drugs SERDs are considered one of the most revolutionary cancer therapies due to their superior clinical profile and ease of administration impacting the quality of life of breast cancer patients positively

This procedure removes growths in the adrenal glands The adrenal glands are found on top of the kidneys and make hormones that are needed to help the body work properly Appendectomy • This procedure removes an infected appendix (the small finger like pouch at the end of the large intestine)

Predictive analytics can be described as a branch of advanced analytics used to make predictions about unknown future events and activities that lead to decision-making. Predictive analytics in healthcare means helping healthcare professionals make more effective and efficient operational and clinical decisions, predict trends, and even find ways to control the spread of disease. This refers to the analysis of current and historical health data that enables.

According to the American Academy of Pediatrics ( Pediatrics is the specialty of medical science that is concerned with the physical, mental, and social health of children from birth to adolescent stage Pediatrics comprises a broad spectrum of health services that range from preventive health care to the diagnosis along with the treatment of acute and chronic diseases

A clinical decision support system ( is a type of health information technology that offers knowledge and person specific data to physicians, employees, patients, and other individuals to support health and medical care A wide range of tools are included in CDSS to improve clinical workflow decision making These tools include, among others, focused patient data reports and summaries, documentation templates, diagnostic support, and contextually relevant reference data

According to World Health Organization ( mental health is defined as a ‘state of well being in which an individual realizes his or her abilities, can cope with the normal stresses of life, can work productively, and can contribute to his or her community • Furthermore, according to MentalHealth gov (a sub division of the U S Department of Health Human Services), mental health comprises emotional, psychological, and social well being

全球痴呆患者超5500万，阿尔兹海默病占比约60%-70%。根据WHO报道，目前全球痴呆症患者已超5500万，其中阿尔兹海默病患者的占比约60%-70%，对应人群在3300-3850万。随着阿尔兹海默病患者的疾病进展，患者将逐步失去独立生活能力，不仅影响患者的生活质量，而且对病患的护理人员、家人和整个社会都有身体、心理、社会和经济影响。

市场行情回顾。9 月（2023 年9 月1 日至9 月30 日），中信生物 医药行业指数上涨4.23%（按照流通市值加权平均计算），同期 沪深300 下跌0.97%，（按照流通市值加权平均计算），跑赢沪深 300 5.2 个百分点，行业整体表现在30 个中信二级行业指数中排 名第3 位，较上月排名快速上升。

全球心衰患病率近年呈增长趋势，左心室辅助装置（LVAD）为晚期心衰的主要治疗手段。无论是中国还是全球，心衰患病率 近年均呈增长趋势，根据CHS（2012-2015）的一项统计，中国年龄≥35岁的心衰患者约为890万人。每年25岁及以上心衰 新发患者约为297万；全球心衰患者约为6400万人。从美国治疗晚期心力衰竭（Advanced heart failure）的指南推荐来看， 晚期心衰主要治疗方法包括心脏移植、左心室辅助装置（或耐用机械循环支持设备）和姑息治疗三种。心脏移植存在等待时 间长的问题，长期机械循环支持设备（MCS）有望成为晚期心衰的主要治疗手段（2a级（美国）/1级（欧洲），仅次于心脏 移植）。其中左心室辅助装置（LVAD）作为耐用MCS的一种，由于其优异的性能，在使用方面占据全球主导地位，作为移植 前过渡或终极治疗。

国内超重与肥胖患者人群基数广泛，健康需求催化 GLP-1 类药物市场持续 增长，同时 GLP-1 类药物在研适应性广泛，进一步打开对应市场空间。近日，诺和诺德司美格鲁肽在此前 CVOT 临床试验成功的基础上又再下一 城，在慢性肾病 FLOW III 期临床研究中因达到预期终点而提前终止临床试验，相应用药人群全球超 1 亿人，市场空间超 200 亿美元。我们认为，GLP-1 类药物目前已在 2 型糖尿病、超重与肥胖、心脑血管疾病、射血分数保留型心衰和慢性肾病中展现出临床获益，可覆盖人群庞大。未来，GLP-1 类药物有望在 NASH 和 AD 等适应症中迎来突破，造福更多患者的同时进一步提升靶点及产业价值。